NUMERO: #20231116

Título: LYMPHOEPITHELIAL CARCINOMA IN THE LOWER LIP: A RARE CASE WITH AN AGGRESSIVE PRESENTATION

Nome do Apresentador: Moisés Willian Aparecido GONÇALVES

Categoria do Trabalho: Painel de caso clínico (PCC)

Área Temática: Patologia Oral

Resumo: Lymphoepithelial Carcinoma (LEC) is a rare and aggressive subtype of head and neck squamous cell carcinoma (HNSCC) that has a similar appearance to the undifferentiated subtype of non-keratinizing nasopharyngeal carcinoma accompanied by a prominent reactive lymphoplasmacytic infiltrate. A 56-year-old male presented to a health service with an ulcerated and painful vegetating lesion with one year of evolution in the lower lip with a previous diagnosis of SCC. Patient reported being an ex-smoker and ex-alcohol user. Tumor resection was performed and a microscopic examination revealed diffuse infiltration of connective tissue by malignant epithelial cells with a dense infiltrate of lymphoplasmacytic cells invading up to the underlying musculature. Perineural invasion and eosinophilic infiltrate were also present. The neoplastic cells were positive for AE1/AE3 and p63 supporting the carcinoma diagnosis. The patient also underwent neck dissection and chemoradiotherapy. There are no signs of recurrence or metastasis after 1 year of follow-up.
Support: CAPES

Autor 1:  Moisés Willian Aparecido GONÇALVES

E-mail 1:  [email protected]

Autor 2:   Reydson Alcides DE LIMA-SOUZA

E-mail 2:  [email protected]

Autor 3 :  Gustavo de Souza VIEIRA

E-mail 3:  [email protected]

Autor 4:  Francisco Augusto Gomes SANTOS

E-mail 4:  [email protected]

Autor 5:  Erika Said Abu EGAL

E-mail 5:  [email protected]

Autor 6:  Albina ALTEMANI

E-mail 6:  [email protected]

Autor 7:  Fernanda Viviane MARIANO

E-mail 7:  [email protected]