NUMERO: #20230949

Título: ATYPICAL HISTOPATHOLOGICAL PRESENTATION OF SYPHILIS

Nome do Apresentador: Natalia Koerich LAUREANO

Categoria do Trabalho: Painel de caso clínico (PCC)

Área Temática: Patologia Oral

Resumo: A 31-years-old woman, COVID-19 infection history, presented a white plaque on the right border of the tongue, measuring 1cm in diameter, 2 months of evolution, and light discomfort. The initial clinical diagnosis was lichen planus versus oral leukoplakia versus trauma. An incisional biopsy was performed, and the histopathological analysis showed the presence of microabscesses on the epithelium, an intense mononuclear inflammatory infiltrate with predominance of plasmocytes in the subepithelial and perivascular region. In some areas, the plasmocytes presented binucleated nuclei and cell atypia. Due to the plasmocyte alteration, the pathologists suggested different diagnoses for investigation: plasma cell mucositis, corticosteroids induced lesion after COVID-19 treatment, cytomegalovirus infection, and syphilis. The clinician was oriented to investigate the patient's syphilis history as a diagnosis of exclusion. After syphilis tested positive, the patient was referred to the doctor for antibiotic treatment. After two months of antibiotic treatment, the white plaque showed complete clinical regression.

Autor 1:  Natalia Koerich LAUREANO

E-mail 1:  [email protected]

Autor 2:   Fernando ANTONINI

E-mail 2:  [email protected]

Autor 3 :  Bruna Jalfim MARASCHIN

E-mail 3:  [email protected]

Autor 4:  Viviane Palmeira DA SILVA

E-mail 4:  [email protected]

Autor 5:  Elena Riet Correa RIVERO

E-mail 5:  [email protected]

Autor 6:  Ricardo Luiz Cavalcanti de ALBUQUERQUE-JUNIOR

E-mail 6:  [email protected]

Autor 7:  Alessandra Dutra DA SILVA

E-mail 7:  [email protected]