NUMERO: #20230879

Título: CENTRAL GIANT CELLS GRANULOMA RECURRENCE AFTER DENOSUMAB USE: A CASE REPORT

Nome do Apresentador: Italo Oliveira BARBOSA

Categoria do Trabalho: Painel de caso clínico (PCC)

Área Temática: Cirurgia e traumatologia bucomaxilofacial

Resumo: Central giant cell granuloma (CGCG) is a benign osteolytic lesion of the jaws of unknown etiology. The behavior, location and extension of the lesion added to the patient´s age will determine the choice of treatment. The aim of this study is to report the case of a 28-year-old patient with expansive CLCG in the left mandibular body and parasymphysis, causing facial asymmetry. Initially, the patient was treated with 6 applications of intralesional injection of triamcinolone (20mg/ml). Subsequently, after treatment failure, the patient underwent therapy with denosumab (120 mg) for 12 months. Five months after the end of therapy with denosumab, computed tomography (CT) showed complete calcification of the lesion. However, 6 months later, a new CT showed radiolucent intraosseous images suggestive of lesion recurrence. We opted for surgical treatment with curettage of the lesion. The patient has been followed up for 5 months without recurrence.

Autor 1:  Italo Oliveira BARBOSA

E-mail 1:  [email protected]

Autor 2:   Beatriz Afonso CHILITI

E-mail 2:  [email protected]

Autor 3 :  Matheus Eiji Warikoda SHIBAKURA

E-mail 3:  [email protected]

Autor 4:  Patricia Verónica AULESTIA-VIERA

E-mail 4:  [email protected]

Autor 5:  Hudson Sá SODRÉ

E-mail 5:  [email protected]

Autor 6:  Patricia Anaya SINHORINI

E-mail 6:  [email protected]

Autor 7:  André Caroli ROCHA

E-mail 7:  [email protected]