NUMERO: #20230602

Título: TONGUE METASTASIS OF BREAST CANCER DIAGNOSED 30 YEARS AFTER THE PRIMARY DIAGNOSIS: A RARE CASE REPORT

Nome do Apresentador: Yuri de Lima MEDEIROS

Categoria do Trabalho: Painel de caso clínico (PCC)

Área Temática: Oncologia

Resumo: A 77-year-old woman presented to Stomatology Department of a hospital complaining of pain and burning tongue swelling, with 90 days of duration. The patient had a diagnosis of breast cancer in 1992, with pulmonary metastasis in 2015. Currently, she was on maintenance treatment with tamoxifen. A slight posterior enlargement indurated on palpation of the tongue was observed. Amyloidosis, sarcoidosis and metastasis were our main diagnosis hypotheses. An incisional biopsy was performed. The histopathological exam revealed an undifferentiated tumor which showed immunoreactivity for GATA-3, estrogen receptor, progesterone receptor, p16, cytokeratin AE1/AE3, and 34BE12 antibodies. The diagnosis was a breast cancer metastasis to the tongue. The patient was referred to clinical oncology. Fulvestrant was initiated, and 45Gy of intensity-modulated radiation therapy was administered. Clinicians should consider metastasis when evaluating patients with a history of malignancy who present oral nodules, regardless of the period of involvement of the primary tumor.

Autor 1:  Yuri de Lima MEDEIROS

E-mail 1:  [email protected]

Autor 2:   Dandara Menezes de Araújo OLIVEIRA

E-mail 2:  [email protected]

Autor 3 :  Osias Vieira de OLIVEIRA FILHO

E-mail 3:  [email protected]

Autor 4:  Laura Luiza Trindade de SOUZA

E-mail 4:  [email protected]

Autor 5:  Clóvis Antonio Lopes PINTO

E-mail 5:  [email protected]

Autor 6:  Graziella Chagas JAGUAR

E-mail 6:  [email protected]

Autor 7:  Fabio Abreu ALVES

E-mail 7:  [email protected]