NUMERO: #20230253

Título: CHRONIC SCLEROSING SIALADENITIS OF THE SUBMANDIBULAR GLAND: A SERIES OF CASES

Nome do Apresentador: Bruno Costa MATOS

Categoria do Trabalho: Painel de pesquisa científica (PPC)

Área Temática: Patologia Oral

Resumo: Objective: To describe the clinicopathological aspects of chronic sclerosing sialadenitis of the submandibular gland and those in the spectrum of IgG4-Related Disease (DR-IgG4).
Study Design: Focal and diffuse Chronic inflammation, periductal fibrosis and sclerosis, reduction of the secretory parenchyma, lymphoid follicles, and those which are common in DR-IgG4 (obliterative phlebitis, storiform fibrosis, dense lymphoplasmacytic infiltrate, eosinophilic infiltrate, presence of sialolith) were identified). All cases were according to the following scores: absent, mild, moderate, and abundant. Demographic and clinical data were also included.
Results: Seventeen cases were identified. The stage 3 was the most frequent, with only three cases in the DR-IgG4 spectrum and 53% had sialoliths. There was a predilection for males, the mean age of 55 years, 3.8 cm on average diameter, equally affecting both sides.
Conclusion: Chronic sclerosing sialadenitis is a rare fibro-inflammatory disease with a varied histopathological spectrum, in which DR-IgG4 must be included in the differential diagnosis.

Autor 1:  Bruno Costa MATOS

E-mail 1:  [email protected]

Autor 2:   Vinicius Rio Verde Melo MUNIZ

E-mail 2:  [email protected]

Autor 3 :  Albina ALTEMANI

E-mail 3:  [email protected]

Autor 4:  Pablo Agostin VARGAS

E-mail 4:  [email protected]

Autor 5:  Valéria Souza FREITAS

E-mail 5:  [email protected]

Autor 6:  Felipe Paiva FONSECA

E-mail 6:  [email protected]

Autor 7:  Jean Nunes DOS SANTOS

E-mail 7:  [email protected]