NUMERO: #20230241

Título: Oral Pyogenic Granuloma: a rare manifestation in cGVHD

Nome do Apresentador: Giovana Dornelas Azevedo ROMERO

Categoria do Trabalho: Painel de caso clínico (PCC)

Área Temática: Oncologia

Resumo: The oral pyogenic granuloma manifestation is rare in chronic graft versus host disease (cGVHD). A 6-year-old, male, was submitted to a second allogeneic hematopoietic stem cell transplantation due to severe aplastic anemia. In D+ 123 he developed oral, ocular, and liver cGVHD. Initially, the oral lesions presented as ulcers on the buccal mucosa and lateral border of tongue with no improvement with topical clobetasol using. The lesions developed as bilateral nodular proliferative tissue with function impairment. The incisional biopsy showed raised area with extensive erosion of the superficial epithelium, associated with a mixed inflammatory process, leukocytic fibrin crust and capillary proliferation, compatible with PG. Nodular lesions were completely removed under general anesthesia and an acetate plate was made to protect the oral mucosa. Two weeks later, patient showed signal of early recurrence. It was started topical clobetasol and the lesions got stable until now (3 months).

Autor 1:  Giovana Dornelas Azevedo ROMERO

E-mail 1:  [email protected]

Autor 2:   Thiago Carvalho dos REIS

E-mail 2:  [email protected]

Autor 3 :  Maria Julia PAGLIARONI

E-mail 3:  [email protected]

Autor 4:  Tatiane Cristina FERRARI

E-mail 4:  [email protected]

Autor 5:  Jorge Esquiche LEÓN

E-mail 5:  [email protected]

Autor 6:  Lara Maria Alencar Ramos INNOCENTINI

E-mail 6:  [email protected]

Autor 7:  Leandro DORIGAN de Macedo

E-mail 7:  [email protected]