NUMERO: #20230235

Título: ORAL VERRUCIFORM XANTHOMA: REPORT OF TWO CASES

Nome do Apresentador: Sebastião Silvério de SOUSA-NETO

Categoria do Trabalho: Painel de caso clínico (PCC)

Área Temática: Estomatologia

Resumo: Oral verruciform xanthoma (OVX) is an uncommon lesion of uncertain origin, allegedly related to trauma, inflammation, or altered immune response. Two cases of OVX are reported. The first patient, a 31-year-old man, with a history of graft-versus-host disease (GVHD) after allogeneic transplantation for acute myelocytic leukemia, presented painful nodular lesions on the lingual dorsum and hard palate, and diffuse lichenoid lesions. The provisional clinical diagnosis was verruciform xanthoma and lichenoid lesions in a patient with GVHD. The patient is currently taking Apixaban for six months due to a pulmonary thromboembolism, what postponed the biopsy. The second patient, also a 31-year-old man, smoker, presented an asymptomatic wart on the lower lip and a plaque on the right buccal mucosa with 1 year of evolution. Clinical appearance suggested verrucous leukoplakia or hyperkeratosis, however, histopathological and immunohistochemical examinations were compatible with OVX. Eight months after excisional biopsy, the patient remains well without recurrence.

Autor 1:  Sebastião Silvério de SOUSA-NETO

E-mail 1:  [email protected]

Autor 2:   Mariana de Pauli PAGLIONI

E-mail 2:  [email protected]

Autor 3 :  Daniel Lobato Ferreira FERRAZ

E-mail 3:  [email protected]

Autor 4:  Ana Luiza Oliveira Corrêa ROZA

E-mail 4:  [email protected]

Autor 5:  Marcio Ajudarte LOPES

E-mail 5:  [email protected]

Autor 6:  Alan Roger SANTOS-SILVA

E-mail 6:  [email protected]

Autor 7:  Pablo Agustin VARGAS

E-mail 7:  [email protected]