NUMERO: #20230181

Título: LONG TERM EVALUATION OF SALIVARY GLANDS AFTER PHOTOBIOMODULATION DURING RADIOTHERAPY FOR HEAD AND NECK CANCER

Nome do Apresentador: Natalia SCHEPANSKI

Categoria do Trabalho: Painel de pesquisa científica (PPC)

Área Temática: Estomatologia

Resumo: The aim of this study was to evaluate the long-term effects of photobiomodulation (PBM) in the prevention of salivary gland hypofunction in patients undergoing treatment with radiotherapy (RT) in the head and neck region. The sample consisted of 28 patients. Stimulated saliva was collected in 4 experimental times: before RT (T1), immediately after RT (T2), 6 to 12 months after (T3) and 13 to 36 months after RT (T4). The following parameters were analyzed: salivary flow (ml/min), pH, and xerostomia (Visual Analogic Scale). PBM was performed during RT (15 to 20 sessions, 2 to 3 times a week) in major and minor salivary glands, 44 points intra (660nm, 100mW, 1J/point) and extraoral (780nm, 100mW, 4J/point). There was no significant decrease in salivary flow between T1 and T2 (p > 0,05), but in T3 and T4 there was a significant reduction in salivary flow (p < 0,05). Xerostomia and the pH suffered variations, but without statistically significant difference. It is concluded that during RT, PBM preserves the function of the salivary glands, preventing a significant reduction in salivary flow and dry mouth, however, after 6 months, the salivary flow is reduced.

Autor 1:  Natalia SCHEPANSKI

E-mail 1:  [email protected]

Autor 2:   Bruna MELO da Silva

E-mail 2:  [email protected]

Autor 3 :  Rafael ZANCAN Mobile

E-mail 3:  [email protected]

Autor 4:  Fernando Luiz ZANFERRARI

E-mail 4:  [email protected]

Autor 5:  José Luís DISSENHA

E-mail 5:  [email protected]

Autor 6:  Laurindo Moacir SASSI

E-mail 6:  [email protected]

Autor 7:  Melissa Rodrigues de ARAÚJO

E-mail 7:  [email protected]