NUMERO: #20230129

Título: TOXIC EPIDERMAL NECROLYSIS AND STEVENS JOHNSON SYNDROME: REPORT OF TWO CASES

Nome do Apresentador: Waleska TYCHANOWICZ Kolodziejwski

Categoria do Trabalho: Painel de caso clínico (PCC)

Área Temática: Odontologia hospitalar

Resumo: Toxic epidermal necrolysis (TEN) and Stevens Johnson syndrome (SJS) are severe skin reactions caused by drug hypersensitivity. The aim is to report 2 cases of drug reactions, outcomes and management. Case 1: 28-year-old male presented skin lesions five days after taking antibiotics for the treatment of syphilis. He evolved with widespread macular and bullous lesions, on the trunk, palms, feet, mouth and peripalpebral region, requiring intensive support. Diagnosis was TEN. Case 2: A 46-year-old male presented pruritic lesions and a nummular macula with a purpuric coloration, five days after the administration of amoxicillin and nimesulide, for a dental procedure. The patient evolved with the presence of hyperchromic blisters that spread genital, oral and palmar region, and flat ulcers. Diagnosis was SJS. The treatment of both included multiprofessional follow-up, corticosteroids, oral hygiene and photobiomodulation. Besides there are no treatment guidelines, a multidisciplinary approach in the management of SJS/NET is mandatory.

Autor 1:  Waleska TYCHANOWICZ Kolodziejwski

E-mail 1:  [email protected]

Autor 2:   Angela Maira GUIMARÃES

E-mail 2:  [email protected]

Autor 3 :  Melissa Tomie Mozena RISSETE

E-mail 3:  [email protected]

Autor 4:  Juliana Lucena SCHUSSEL

E-mail 4:  [email protected]

Autor 5:  José Miguel AMENÁBAR

E-mail 5:  [email protected]

Autor 6:  Heliton Gustavo de LIMA

E-mail 6:  [email protected]

Autor 7:  Melissa Rodrigues de ARAUJO

E-mail 7:  [email protected]