NUMERO: #20230117

Título: A SYSTEMATIC REVIEW OF CLINICAL FEATURES, DIAGNOSIS AND TREATMENT OF MUCOUS MEMBRANE PEMPHIGOID AND PEMPHIGUS VULGARIS

Nome do Apresentador: Hannah Gil de Farias MORAIS

Categoria do Trabalho: Painel de Revisões narrativas ou sistemáticas (PRN)

Área Temática: Estomatologia

Resumo: Objective: Understand and evaluate the clinical and demographic profile, diagnostic methods, and treatment of patients with pemphigus vulgaris (PV) and mucous membrane pemphigoid (MMP). Study Design: A database search was performed and studies describing cases of PV and MMP diagnosed by direct immunofluorescence that exhibited intraoral manifestations were included. Results: Thirty-two articles were included (18 studies on PV and 15 on MMP). Most patients with PV (64%) and MMP (81.3%) were women in the fifth and sixth decade of life, respectively. The mouth was the primary site of involvement both in PV (71.4%) and in MMP (91%). The buccal mucosa and gingiva were the most frequently affected intraoral sites in PV (30%) and MMP (64.2%), respectively. Direct immunofluorescence was positive for IgG in all cases of two conditions. The treatment of choice was systemic corticosteroid therapy for patients with PV (50%) and topical treatment for patients with MMP (53.7%). Conclusion: Clinical differences and in the results of diagnostic tests allow us to trace the clinical, demographic, and diagnostic profile of PV and MMP that contributes to differential diagnosis and therapeutic management in an attempt to better control these diseases and to ensure the quality of life of affected patients.

Autor 1:  Hannah Gil de Farias MORAIS

E-mail 1:  [email protected]

Autor 2:   Carla Samily de OLIVEIRA

E-mail 2:  [email protected]

Autor 3 :  Maurília Raquel de Souto MEDEIROS

E-mail 3:  [email protected]

Autor 4:  Leonardo Magalhães CARLAN

E-mail 4:  [email protected]

Autor 5:  Éricka Janine Dantas da SILVEIRA

E-mail 5:  [email protected]

Autor 6:  Patrícia Teixeira de OLIVEIRA

E-mail 6:  [email protected]

Autor 7:  Roseana de Almeida FREITAS

E-mail 7:  [email protected]