NUMERO: #20230096

Título: PEMPHIGUS VULGARIS: REFRACTORY SKIN LESIONS DIAGNOSED FROM ORAL LESIONS

Nome do Apresentador: Weslaynne Nepomuceno Lemes de Paula MORAIS

Categoria do Trabalho: Painel de caso clínico (PCC)

Área Temática: Estomatologia

Resumo: A 66-years old white female presented with a 2-month history of mouth ulcers. Her gums were bleeding and causing discomfort, making oral hygiene difficult. She also reported reddish skin blisters on her back for over a year. The patient reported being seen by several specialists who were unable to reach a diagnosis, and at the time of the examination, a patch test investigation was being conducted due to the hypothesis of an allergy. On intraoral examination, positive Nikolsky sign was observed, with the epithelium detaching easily (attached video). A biopsy was taken for direct immunofluorescence, which lead to a diagnosis of Pemphigus Vulgaris. The patient is currently under medical follow-up with oral corticosteroid (Prednisone) therapy and mouth rinses with 0.05% clobetasol propionate, as well as photobiomodulation, showing significant improvement with disappearance of cutaneous lesions and
improvement of gingival lesions.

Autor 1:  Weslaynne Nepomuceno Lemes de Paula MORAIS

E-mail 1:  [email protected]

Autor 2:   Maria Letícia CINTRA

E-mail 2:  leticia.unicamp.br

Autor 3 :  Maria Luzia dos Santos Firmino MORAES

E-mail 3:  [email protected]

Autor 4:  Victor MONTALLI

E-mail 4:  [email protected]

Autor 5:  Marcelo SPERANDIO

E-mail 5:  [email protected]

Autor 6:  José Luiz Cintra JUNQUEIRA

E-mail 6:  [email protected]

Autor 7:  Paulo de Camargo MORAES

E-mail 7:  [email protected]