NUMERO: #20230088

Título: PLEOMORPHIC ADENOMA WITH EXTENSIVE SQUAMOUS METAPLASIA AND KERATIN CYST FORMATION: AN ATYPICAL HISTOLOGICAL PRESENTATION

Nome do Apresentador: Natália Cristina Trentin BORDIGNON

Categoria do Trabalho: Painel de caso clínico (PCC)

Área Temática: Patologia Oral

Resumo: Pleomorphic adenoma (PA) is a benign salivary gland tumor characterized by genetic heterogeneity and diversity of morphological aspects. PA has epithelial, myoepithelial and stromal components. PA with extensive squamous metaplasia can mimic malignancies presenting a diagnostic challenge. A 35-year-old female patient complained of painless swelling in the left palate with 5 years of evolution. After the incisional biopsy, microscopic analysis revealed a benign neoplasm of glandular origin consisting of epithelial and myoepithelial cells arranged in nests, cords and ductal structures. The lesion showed multiple cystic formations lined by squamous epithelium and filled with keratin. The final diagnosis of PA was obtained. The patient was referred for surgical removal of the lesion. After 15 months of follow-up, the patient had no recurrences.

Autor 1:  Natália Cristina Trentin BORDIGNON

E-mail 1:  [email protected]

Autor 2:   Angélica REINHEIMER

E-mail 2:  [email protected]

Autor 3 :  Fernanda Marcello SCOTTI

E-mail 3:  [email protected]

Autor 4:  Ana Guadalupe GAMA-CUELLAR

E-mail 4:  [email protected]

Autor 5:  Filipe Modolo SIQUEIRA

E-mail 5:  [email protected]

Autor 6:  Ricardo Luiz Cavalcanti de ALBUQUERQUE JUNIOR

E-mail 6:  [email protected]

Autor 7:  Rogério GONDAK

E-mail 7:  [email protected]