NUMERO: #20230023

Título: MORPHOLOGICAL CRITERIA TO VITILIGO DIAGNOSIS IN A COHORT FROM A MUNICIPALITY OF GOIAS SOUTHWEST

Nome do Apresentador: Rômulo de Brito CAVALCANTI

Categoria do Trabalho: Painel de pesquisa científica (PPC)

Área Temática: Dermatologia

Resumo: Objective: Considering the heterogeneity of clinical and histopathological presentation of vitiligo and other depigmented lesions, this is study aims to study the morphological criteria for diagnosing vitiligo in skin and perioral in a local cohort of patients. Study design: Were analyzed 25 skin and perioral biopsies diagnosed as suggestive of vitiligo, between the years 2009 and 2021, performed by a private pathology laboratory in Southwest of Goiás. After histological processing, slides were analyzed considering morphological parameters described in the literature. Results: Inflammatory infiltrate criteria, both perivascular and in the dermis and epidermis, can be used as indicative of the inflammatory nature of the depigmentation, helping to differentiate it from other entities such as nevus depigmentosus. Other findings such as degeneration of the basal layer, spongiosis, basal vacuolation, dyskeratosis, hyperkeratosis, thinned epidermis and absence of dermal papillae can also be used as criteria indicative of vitiligo lesions. Conclusion: Despite identifying criteria suggestive of the disease, the study demands the expansion of the sample for a better characterization of the findings. Furthermore, the importance of correlating anatomopathological findings with clinical information is reinforced to ensure greater data reliability.

Autor 1:  Rômulo de Brito CAVALCANTI

E-mail 1:  [email protected]

Autor 2:   Mariana Rodrigues FERREIRA

E-mail 2:  [email protected]

Autor 3 :  Edismair Carvalho GARCIA

E-mail 3:  [email protected]

Autor 4:  Gabriel Silva SOARES

E-mail 4:  [email protected]

Autor 5:  Vinícius Gonçalves de SOUZA

E-mail 5:  [email protected]

Autor 6:  Aparecida de Lourdes CARVALHO

E-mail 6:  [email protected]

Autor 7:  Carla Silva Siqueira MIRANDA

E-mail 7:  [email protected]