NUMERO: #20230008

Título: Inferior alveolar nerve paresthesia as the first sign of Multiple Myeloma - case report

Nome do Apresentador: Estephani MARTINS Barcellos de Carvalho

Categoria do Trabalho: Painel de caso clínico (PCC)

Área Temática: Patologia Oral

Resumo: Multiple myeloma (MM) is a neoplastic proliferation of plasma cells with systemic repercussion and osteolytic lesions - that may cause inferior alveolar nerve (IAN) paresthesia, once located in the mandible. Therefore, we report a case of a 52-year-old female that was referred for evaluation of a periapical lesion and IAN paresthesia. Extraoral physical exam showed mild swelling on the right hemiface. Intraorally, there was no alteration. A panoramic radiography revealed an ill-defined radiolucency located in the right mandibular ramus. Blood tests showed the presence of M-protein in the serum and hypocalcemia. An incisional biopsy was performed under local anesthesia and histological and immunohistochemical diagnosis was of Plasmacytoma. The patient was referred to the hematologist to investigate other lesions and a costal arch biopsy also diagnosed plasma cell tumor. Thus, MM diagnosis was established. Dentists should be aware of MM as oral manifestations could be the first signs of the disease.

Autor 1:  Estephani MARTINS Barcellos de Carvalho

E-mail 1:  [email protected]

Autor 2:   Bruno Teixeira Gonçalves RODRIGUES

E-mail 2:  [email protected]

Autor 3 :  Fábio RAMOA Pires

E-mail 3:  [email protected]

Autor 4:  Paulo José d´Albuquerque MEDEIROS

E-mail 4:  [email protected]

Autor 5:  Marcele CRUZ da Silva

E-mail 5:  [email protected]